What is CAR T-Cell Therapy?

CAR T-Cell Therapy, an immunotherapy sometimes called immune effector cell therapy, is a novel therapy that programs a patient’s immune system to recognize and fight cancer. The immune system is responsible for ridding the body of abnormal cells that are foreign (like cancer) or infected. T-lymphocytes (T-Cells) are a type of cell responsible for killing abnormal cells. During the CAR T-Cell treatment process, T-Cells are drawn from a patient's blood and genetically modified to recognize the patient’s cancer cells when reinfused.

Introduction to CAR T-Cell Therapy Overview: Watch this animated video to understand the science, process and benefits of CAR T-Cell Therapy, often called immune effector cell therapy. Many Sarah Cannon Blood Cancer Networks program offer CAR T-Cell options for patients.

What is a Blood and Marrow Transplant?

When diagnosed with blood cancer, treatment options may include a blood or marrow transplant (BMT), also known as a stem cell transplant.

The Sarah Cannon Blood Cancer Network is one of the largest providers of blood and marrow transplants, conducting more than 1,200 transplants annually.

Blood and Marrow Transplant 101

Blood & Marrow Transplant 101: Watch this animated video to understand the process of a blood and marrow, or stem cell, transplant. As a member of the Sarah Cannon Blood Cancer Network, our program has access to a number of quality, infrastructure, training and research resources.

Remember, each transplant experience is unique - no two patients are exactly alike. The pathway may depend on many factors, including:

  • Type of transplant
  • Overall health
  • Disease status

What Should I expect with a Blood and Marrow Transplant?

Watch these videos from Sarah Cannon partner, Be The Match®, to learn more about blood and marrow transplants.

Where do Cells for a Transplant Come From?

Bone marrow, peripheral blood stem cell (PBSC), and cord blood provide different sources of cells for transplantation.

What is HLA Matching?

Why a good Human Leukocyte Antigen (HLA) match is critical.

What is Engraftment?

Engraftment of donated cells is an important recovery milestone.

What is GVHD?

Graft-Versus-Host Disease (GVHD) is a common side effect of an allogeneic transplant.

About Be The Match®

Be The Match®, a Sarah Cannon partner, has a team dedicated to supporting patients, caregivers, family members and friends, before, during and after a transplant. They offer confidential one-on-one support, financial guidance and free educational resources. Visit BeTheMatch.org/LearnTheBasics to view more videos to help you learn about and prepare for transplant.